Work

Anti-Cancer Activity of Derivatives of 1,3,4-Oxadiazole

Year: 2018

Type: review

Abstract: Compounds containing 1,3,4-oxadiazole ring in their structure are characterised by multidirectional biological activity. Their anti-proliferative effects associated with various mechanisms, such as inhibition of growth factors, enzymes, kinases and others, deserve attention. The activity of these compounds was tested on cell lines of various cancers. In most publications, the most active derivatives of 1,3,4-oxadiazole exceeded the effect of reference drugs, so they may become the main new anti-cancer drugs in the future.

Source: Molecules

DOI: 10.3390/molecules23123361

Authors: Teresa Glomb, Karolina Szymankiewicz, Piotr Świątek

Institution: Wroclaw Medical University

Language: English

Topic: Structural and Chemical Analysis of Organic and Inorganic Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,258