Work

Polymer conjugation of proteins as a synthetic post-translational modification to impact their stability and activity

Year: 2018

Type: article

Abstract: , and introduce stimuli responsiveness. Bioconjugation has resulted to modulated thermal stability, chemical stability, storage stability, half-life and reusability. In this review we aim to provide a brief state of the field, highlight a wide range of behaviors caused by polymer conjugation, and provide areas of future work.

Source: Polymer Chemistry

DOI: 10.1039/c8py01399c

Authors: Thaiesha A. Wright, Richard C. Page, Dominik Konkolewicz

Institution: Miami University

Language: English

Topic: Advanced Polymer Synthesis and Characterization

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Institute of General Medical Sciences, Division of Materials Research

Awards: G2677953987, G5210186636, Function and Pathway outcomes of Dynamic Protein Structures