Work

Human ESC-Derived Chimeric Mouse Models of Huntington’s Disease Reveal Cell-Intrinsic Defects in Glial Progenitor Cell Differentiation

Year: 2018

Type: article

Source: Cell stem cell

DOI: 10.1016/j.stem.2018.11.010

Authors: Mikhail Osipovitch, Andrea Asenjo Martinez, John N. Mariani, Adam Cornwell, Simrat Dhaliwal, Lisa Zou, Devin Chandler-Militello, Su Wang, Xiaojie Li, Sarah-Jehanne Benraiss, Robert Agate, Andrea Lampp, Abdellatif Benraiss, Martha S. Windrem, Steven A. Goldman

Institutions: University of Copenhagen, University of Rochester Medicine, Rigshospitalet

Language: English

Topic: Genetic Neurodegenerative Diseases

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: CHDI Foundation, Dr. Miriam and Sheldon G. Adelson Medical Research Foundation, Lundbeckfonden, Novo Nordisk Fonden, National Institute of Mental Health, National Institute of Neurological Disorders and Stroke

Awards: Transcriptional Determinants of the Fate Trajectories of Single Human Glial Progenitor Cells in Response to Demyelination in Vivo, G3259086182, An iPSC based humanized mouse model of dysmyelination in schizophrenia, A Humanized Mouse Model of Astrocytic Pathology in Schizophrenia, G7108706085

OpenAlex ID: W2904655759

FWCI: 2.836

Cites: 47

Cited by: 114

Related to: 10