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Advanced Methods for Accessing Protein Shape-Shifting Present New Therapeutic Opportunities

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Year: 2018
Type: review
Source: Trends in Biochemical Sciences
DOI: 10.1016/j.tibs.2018.11.007
Authors: Catherine R. Knoverek, Gaya K. Amarasinghe, Gregory R. Bowman
Institution: Washington University in St. Louis
Language: English

Topic: Protein Structure and Dynamics
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: green

Funders: National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases
Awards: Allosteric impact of non-active-site mutations on enzymatic function, Therapeutics Targeting Filoviral interferon-antagonist and replication functions, Mechanisms of evasion of the innate and adaptive immune responses to filoviruses, Multi-platform High Throughput Screens for Filoviral Replication Inhibitors, Novel VP30-host Interactions that Negatively Regulate Ebola Virus Infection, Molecular Mechanisms of Filoviral-host Interactions
OpenAlex ID: W2904865562
FWCI: 0.372
Cites: 68
Cited by: 52
Related to: 10
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