Work

Visualizing the vasculature of the entire human eye posterior hemisphere without a contrast agent

Year: 2018

Type: article

Abstract: The platform described here combines the non-invasive measurement of the retina/choroid structure and ocular blood flow based on optical coherence tomography (OCT) and wide-field semi-quantitative global flow visualization using line-scanning Doppler flowmetry (LSDF). The combination of these two imaging modalities within the same platform enables comprehensive assessment of blood flow in the retina and choroid in animals and human subjects for diagnostic purposes. Ultra-widefield vasculature visualization is demonstrated here for the first time without injecting additional contrast agents and based only on the motion of particles within the vasculature.

Source: Biomedical Optics Express

DOI: 10.1364/boe.10.000167

Authors: Mircea Mujat, Yang Lu, Gopi Maguluri, Youbo Zhao, Nicusor Iftimia, R. Daniel Ferguson

Institution: Physical Sciences (United States)

Language: English

Topic: Optical Coherence Tomography Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,913