Quantitative susceptibility mapping (QSM) evaluation of infantile neuroaxonal dystrophy
Year: 2018
Type: article
Study design: Case Report
Abstract: We present the first case of twins with infantile neuroaxonal dystrophy evaluating brain iron deposition using quantitative susceptibility mapping (QSM). A 6-year-old boy who was normal at birth had psychomotor regression and hypotonia from 2-years-old. Brain MRI showed low intensity areas in globus pallidus (GP) and substantia nigra (SN) on T2* weighted imaging. QSM values of GP and SN were 0.19 and 0.29 ppm, respectively. His twin brother showed almost the same imaging findings. Follow-up MRI revealed increase of QSM value in GP and SN.
Source: BJR|case reports
Authors: Takuya Fujiwara, Yoshiyuki Watanabe, Hisashi Tanaka, Hiroto Takahashi, Shin Nabatame, Wang Yi, Noriyuki Tomiyama
Institutions: The University of Osaka, Cornell University
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $658
OpenAlex ID: W2905038115