Year: 2018
Type: article
Abstract: With all the recent excitement about the resurgence of clinical research on the classic serotonergic psychedelics, in what has been labeled the psychedelic renaissance, it is easy to overlook a concurrent revolution taking place in the field of ketamine research.More than 50 years have passed since the synthesis of ketamine, and it remains today the most widely available compound with psychedelic propertiesnearly ubiquitously approved for both research and clinical use.Ketamine has recently proved to be highly effective for depression and suicidality, with a rapid onset of effect.Despite currently being the leading cause of disability in the world, there have been no major advances in depression treatment, since the selective serotonin reuptake inhibitors of the 1980s.In the context of this stagnation, research on ketamine has been met with understandable enthusiasm, typified by former director of the National Institute of Mental Health (NIMH) Thomas Insel's proclamation that ketamine "might be the most important breakthrough in antidepressant treatment in decades."Two books, Ketamine for Treatment-Resistant Depression: The First Decade of Progress edited by Sanjay J.
Source: Journal of Psychedelic Studies
Author: Lowan H. Stewart
Language: English
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2905200637