Work

Point-of-care HIV RNA testing and immediate antiretroviral therapy initiation in young adults seeking out-patient care in Kenya

Year: 2018

Type: article

Abstract: : We evaluated outcomes of an HIV-1-testing intervention using rapid HIV tests followed by point-of-care Xpert Qual testing for HIV-1 RNA. Of 706 young urgent-care seeking participants evaluated, 24 (3.4%) had chronic HIV (antibody-positive), 3 (0.4%) acute HIV-1 (Qual-positive, antibody-negative), and 3 (0.4%) early HIV-1 infection (Qual-positive, antibody-discordant). Overall, 21 (70.0%) diagnosed patients started antiretroviral therapy after a median of 4 days (range 0-71). HIV-1 RNA testing led to an increase in confirmed diagnoses by 25%.

Source: AIDS

DOI: 10.1097/qad.0000000000002110

Authors: Eduard J. Sanders, Oscar Chirro, Clifford Oduor, Juma Mangi, Elizabeth Wahome, Matthew A. Price, Hubert C. Gelderblom, Elisabeth M. van der Elst, Susan M. Graham

Institutions: Kenya Medical Research Institute, University of Oxford, KEMRI-Wellcome Trust Research Programme, Wellcome Trust, International AIDS Vaccine Initiative, University of Washington

Language: English

Topic: HIV/AIDS Research and Interventions

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: United States Agency for International Development, International AIDS Vaccine Initiative, Wellcome Trust, National Institutes of Health, National Institute of Allergy and Infectious Diseases

Awards: Impact of a novel screening program to detect acute and prevalent HIV infection and reduce HIV transmission, G4083274430, G4156438909, Kenya KWTRP Major Overseas Programme, G704771751, Core Support for the East African Major Overseas Programme

OpenAlex ID: W2905801036

FWCI: 0.916

Cites: 13

Cited by: 6

Related to: 10