Work

The state of the microcirculation of the skin in patients with pulmonary hypertension due to congenital heart defects

Year: 2018

Type: article

Abstract: Aim - to assess the state of microcirculation in the skin in patients with pulmonary hypertension due to congenital heart defects (PH-CHD). Material and methods. The study was performed using laser Doppler flowmetry and capillaroscopy in 25 patients with PH-CHD and a control group (n=25). Results. Patients with PH-CHD have a low blood saturation of 90.1 % and 97.2 % (<0.05), a high amplitude of myogenic vasomotions of 0.49 PU and 0.26 PU (<0.05), pulsatile 0.14 PU and 0.11 PU (<0.05) and respiratory associated blood flow fluctuations of 0.24 PU and 0.13 PU (<0.05), respectively. Against this background, there is no evidence of fluid retention in the tissue. Conclusions. Changes in microcirculation are compensatory in the conditions of systemic hypoxia, caused by violations of hemodynamics in the heart and a small circle of blood circulation.

Source: Regional blood circulation and microcirculation

DOI: 10.24884/1682-6655-2018-17-3-65-70

Authors: E. V. Dolgova, A. A. Fedorovich, T. M. Martynyuk, A. N. Rogoza, I. E. Chazova

Institutions: National Medical Research Center of Cardiology, Russian Academy of Sciences, Institute of Biomedical Problems, National Research Center for Preventive Medicine

Language: English

Topic: Pulmonary Hypertension Research and Treatments

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W2905873544

FWCI: 0.169

Cites: 9

Cited by: 2

Related to: 10