The role of hydrogen in Alzheimer’s disease
Year: 2018
Type: review
Abstract: Alzheimer's disease is one of the most common neurodegenerative diseases in the elderly. It is often manifested as learning and memory impairment, cognitive function decline, normal social and emotional disorders. However, for this high-risk common disease, there is currently no effective treatment, which has plagued many clinicians. As a new type of medical therapeutic gas, hydrogen has attracted much attention recently. As a recognized reducing gas, hydrogen has shown great anti-oxidative stress and anti-inflammatory effect in many cerebral disease models. It can ameliorate neuronal damage, maintain the number of neurons, prolong the lifespan of neurons, and ultimately inhibit disease progression. Therefore, the role and mechanism of hydrogen in the pathological process of Alzheimer's disease will be discussed in this paper.
Source: Medical Gas Research
Authors: Xin Tan, Fang Shen, Wan-Li Dong, Yi Yang, Gang Chen
Institution: First Affiliated Hospital of Soochow University
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2906177600