Laboratory Diagnosis of Neonatal Herpes Simplex Virus Infections
Year: 2019
Type: review
Abstract: Herpes simplex virus (HSV) is a common and often benign infection in humans; although it less commonly affects newborns, infection in this age group can be devastating. Newborns often present with nonspecific clinical findings, making timely and accurate diagnosis of infection critical. A wide variety of tests are available for detecting herpes simplex virus infection, but only a subset are useful and validated in the newborn population. The current review summarizes available diagnostic testing for neonatal disease, including discussing limitations, unmet needs, and emerging data on molecular testing methods.
Source: Journal of Clinical Microbiology
DOI: 10.1128/jcm.01460-18
Authors: William J. Muller, Xiaotian Zheng
Institutions: Northwestern University, Lurie Children's Hospital
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2906751013