Year: 2018
Type: article
Abstract: Molybdenum-cofactor biosynthesis protein 1 catalyzes the first step in the synthesis of molybdenum cofactor (Moco), which is conserved across taxa and present both in prokaryotes and in eukaryotes. The effects of Mocs1 -upregulation on Drosophila lifespan were determined using the GAL4-UAS system to drive Mocs1 expression. Driven females lived significantly longer than controls (p=5.7x10 -6 , p=9.0x10 -4 ) while males did not show increased lifespan (p=0.49, p=1.8x10 -5 ). The data suggest a link between Mocs1 and lifespan which has not been previously explored.
Author: Michael Lee
Language: English
Subfield: Aging
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2907428181