Pre-exposure prophylaxis for HIV prevention preferences among young adult African American men who have sex with men
Year: 2018
Type: article
Abstract: Pre-exposure prophylaxis (PrEP) is effective in preventing HIV infections among men who have sex with men (MSM). PrEP uptake and adherence remain low and product preferences are unknown, especially among young African American MSM who are most at-risk. We conducted 26 qualitative interviews from 2014-2016 among young adult HIV-negative African American MSM regarding PrEP product preferences in Missouri. While the pill and injectable were most liked of all modalities, about a quarter preferred rectal products or patches. Most participants preferred a long-acting injectable (LAI) to daily oral pills due to better medication adherence and a dislike for taking pills. Many participants preferred daily oral pills to on-demand oral PrEP due to the inability to predict sex and the perception that insufficient time or medication would not achieve HIV protection with on-demand. A fear of needles and the perception that there would not be therapeutic levels for a long duration were concerns with injectable PrEP. Study findings highlight the need for a range of prevention options for African American MSM and can inform PrEP product development as well as dissemination and implementation efforts.
Source: PLoS ONE
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,382
Funders: Gilead Sciences, Washington University in St. Louis, Foundation for Barnes-Jewish Hospital, Institute of Clinical and Translational Sciences, ViiV Healthcare, Alvin J. Siteman Cancer Center, National Institutes of Health, National Institute of Mental Health, National Center for Advancing Translational Sciences
Awards: G1190814588, G1278655010, G2355005229, Washington University Institute of Clinical and Translational Sciences, Characterizing the HIV pre-exposure prophylaxis care continuum for African American and Hispanic/Latino men who have sex with men, Washington University Institute of Clinical and Translational Sciences, G7501977493, Brown University Community and Clinical Research Training Program, Washington University Institute of Clinical and Translational Sciences, Washington University Institute of Clinical and Translational Sciences (KL2), G951152184
OpenAlex ID: W2907671687