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TET2 stabilization by 14-3-3 binding to the phosphorylated Serine 99 is deregulated by mutations in cancer

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Year: 2019
Type: article
Source: Cell Research
DOI: 10.1038/s41422-018-0132-5
Authors: Hao Chen, Dingdang Yu, Rui Fang, Kimberlie Rabidou, Di Wu, Di Hu, Peilin Jia, Zhongming Zhao, Zhiping Wu, Junmin Peng, Yang Shi, Yujiang Geno Shi
Institutions: Boston Children's Hospital, Shanghai Medical College of Fudan University, Harvard University, Fudan University, Zhongshan Hospital, Brigham and Women's Hospital, The University of Texas Health Science Center at Houston, St. Jude Children's Research Hospital
Language: English

Topic: Epigenetics and DNA Methylation
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences
Awards: G2704578558, De-Regulation of 5hmC/TET2 Tumor Suppressor under Anti-Estrogen Therapy, Post Translational Regulation of TET2 Function by Glucose Signaling, G765206750
OpenAlex ID: W2907917919
FWCI: 0.579
Cites: 11
Cited by: 7
Related to: 10
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