Work

Mapping the human pulmonary venoatrial junction with optical coherence tomography

Year: 2019

Type: article

Abstract: Imaging guidance provided by optical coherence tomography (OCT) could improve the outcomes of atrial fibrillation (AF) ablation by providing detailed structural information of the pulmonary veins, which are critical targets during ablation. In this study, stitched volumetric OCT images of venoatrial junctions from post-mortem human hearts were acquired and compared to histology. Image features corresponding to venous media and myocardial sleeves, as well as fiber orientation and fibrosis, were identified and found to vary between veins. Imaging of detailed tissue architecture could improve understanding of the AF structural substrate within the pulmonary veins and assist the guidance of ablation procedures.

Source: Biomedical Optics Express

DOI: 10.1364/boe.10.000434

Authors: Theresa H. Lye, Vivek Iyer, Charles C. Marboe, Christine P. Hendon

Institutions: Columbia University, Columbia University Irving Medical Center

Language: English

Topic: Optical Coherence Tomography Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,913