Work

Glycosylation of the HIV-1 Env V1V2 Loop to Form a native-like Structure May not be Essential with a Nanoparticle Vaccine

Year: 2019

Type: article

Abstract: vaccination with unglycosylated HIV-1 Env V1V2 antigens that fold into native-like confirmation may generate functional antibodies at higher titers with higher affinity, ideally leading to a better vaccine candidate "

Source: Future Virology

DOI: 10.2217/fvl-2018-0174

Authors: Christopher P Karch, Gary R Matyas, Peter Burkhard, Zoltan Beck

Institutions: Henry M. Jackson Foundation, Walter Reed Army Institute of Research

Language: English

Topic: HIV Research and Treatment

Subfield: Virology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: U.S. Department of Defense, National Institutes of Health, National Institute on Drug Abuse

Awards: Development of a Practical Heroin-HIV Vaccine, G4119534169, G5850682332, US MILITARY HIV RESEARCH

OpenAlex ID: W2908754768

FWCI: 0.28

Cites: 40

Cited by: 3

Related to: 10