Attention-deficit/hyperactivity disorder: An integrated developmental psychopathology and Research Domain Criteria (RDoC) approach
Year: 2019
Type: review
Abstract: Attention-deficit/hyperactivity disorder (ADHD) is characterized by heterogeneous behaviors and symptoms, developmental trajectories, and treatment response. Isolating intermediate phenotypes that are superior to current DSM-based nosology in order to explain such heterogeneity is integral to enhancing etiological theory, improving clinical assessment, predicting treatment response, and developing tailored treatments. To this end, this review provides an integrated developmental psychopathology and National Institute of Mental Health Research Domain Criteria (RDoC) approach to ADHD. In particular, associations between ADHD and RDoC domains of cognition (specifically working memory) and positive valence (reward anticipation/delay/receipt) are discussed. These domains are examined across behavioral and neurocircuitry levels of analysis and placed within a developmental context via examining associations among RDoC domains, relevant features of ADHD, and environmental correlates implicated across development. Limitations of the existing literature and proposed future directions are explored. Importantly, future work should focus on novel approaches that account for developmental shifts in functioning of relevant RDoC domains over time, as well as further examination of the interaction across RDoC domains and levels of analysis.
Source: Comprehensive Psychiatry
Authors: Erica D. Musser, Joseph S. Raiker
Institution: Florida International University
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,100
Awards: G1438172959, G2183174672, Examining Tolerance to CNS Stimulants in ADD, G3021515229, G3113647773, G383914308, Heterogeneity in ADHD: Autonomic, Behavior, Emotion, and Treatment Response, FUNCTIONAL CHARACTERISTICS OF NEURONAL NICOTINIC, G5056939942, G5197324266, A novel examination of the neurobiological deficits underlying increased reaction time variability in children with ADHD., Emotional Systems in Attention-Deficit/Hyperactivity Disorder, G786432218, MRI: Development of an Integrated Neuroimaging Instrument with Temporal and Spatial Alignments for Brain Research
OpenAlex ID: W2909142036