Get started
Work

Cross-antigenic and Immunogenic Features of Canonical and New Genogroups of Enterovirus 71

Year: 2018
Type: article
Abstract: The specificity of examined sandwich-ELISA variants was high, the sensitivity widely varied.The best result (7 ng/ml of purified AV 6 type) was obtained with capture MAbs #1 and PX conjugate of these MAbs.For AV antigens detection in infected cell the most promising is MAbs #2 FITC conjugate that allows to detect AV of epidemic types in infected cells in form of nuclear localized clear fluorescence.Usage of MAbs for development of high sensitivity and specificity test-kits for differential diagnosis of AV infection provides new possibilities for medical practice.Diagnostic properties of developed sandwich-ELISA and MAbs #2 FITC conjugate will be investigated with clinical samples. 3.48
DOI: 10.15789/2220-7619-2018-4-3.50
Authors: R. Volle, L. Luo, R. Razafindratsimandresy, S. SadeuhMba, I. Gouandjika, P. Horwood, V. Duong, P. Buchy, Z. Huang, E. Duizer, J. Martin, L. A. Chakrabarti, P. Dussart, F. Delpeyroux
Institutions: Institut Pasteur, Institut Pasteur de Madagascar, Centre Pasteur du Cameroun, Institut Pasteur de Bangui, Institut Pasteur du Cambodge, Institut Pasteur of Shanghai, National Institute for Public Health and the Environment, National Institute for Biological Standards and Control
Language: English
Field: Medicine
Open Access status: diamond
OpenAlex ID: W2910276495
FWCI:
Cites:
Cited by:
Related to: 10