A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion
Year: 2019
Type: article
Source: Cancer Cell
Authors: Shanye Yin, Rutendo G. Gambe, Jing Sun, Aina Zurita Martinez, Zachary J. Cartun, Fara Faye D. Regis, Youzhong Wan, Jean Fan, Angela N. Brooks, Sarah E.M. Herman, Elisa ten Hacken, Amaro Taylor-Weiner, Laura Z. Rassenti, Emanuela M. Ghia, Thomas J. Kipps, Esther A. Obeng, Carrie L. Cibulskis, Donna Neuberg, Dean R. Campagna, Mark D. Fleming, Benjamin L. Ebert, Adrian Wiestner, Ignaty Leshchiner, James A. DeCaprio, Gad Getz, Robin Reed, Ruben D. Carrasco, Catherine J. Wu, Lili Wang
Institutions: Harvard University, Dana-Farber Cancer Institute, Broad Institute, University of California, Santa Cruz, National Institutes of Health, National Heart, Lung, and Blood Institute, University of California San Diego, Moores Cancer Center, St. Jude Children's Research Hospital, Boston Children's Hospital, Brigham and Women's Hospital, Dana-Farber Brigham Cancer Center, Massachusetts Institute of Technology, City of Hope, Beckman Research Institute
Language: English
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funders: National Science Foundation, Lymphoma Research Foundation, International Business Machines Corporation, Merck, Leukemia and Lymphoma Society, Celgene, Constellation Pharmaceuticals, National Institutes of Health, U.S. Public Health Service, Pharmacyclics, National Heart, Lung, and Blood Institute, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Diabetes and Digestive and Kidney Diseases
Awards: Human Cancer Suppressor Functions of Protein Phosphatase 2A, G1395449595, Cooperation of SF3B1 mutations and ATM deletions in the pathogenesis of chronic lymphocytic leukemia, G1581977058, G1791404784, G1864025506, G1878704239, G226688381, G2699776391, G3007936770, G3032743408, G3293357216, G3431058262, G3966681288, G4370319101, G4493190077, G4561983161, G4648539572, G4663567540, (PQ8) Genetically faithful murine models for studying disease progression in chronic lymphocytic leukemia, G5449796690, G5544403951, G5843292180, G6265436507, The role of the SF3B1 splicing factor in chronic lymphocytic leukemia, G6842955338, SPORE in Myeloid Malignancies, G792176338, Chronic Lymphocytic Leukemia Research Consortium, Graduate Research Fellowship Program (GRFP), RB-Related Proteins and Polyomavirus Large T antigen Transformation, G9000047808, G9000067295, G9000100137, G9000177301, G9000186004, G9000248136, G9000256811, G9000312423, G9000312532, Comprehensive dissection of the CLL genome & phenome to improve patient outcomes, G944802235
OpenAlex ID: W2911426599