Year: 2018
Type: article
Abstract: Salmonella enterica subspecies enterica serovar Typhi (Salmonella Typhi) is the cause of typhoid fever and a human host-restricted organism. Our understanding of the global burden of typhoid fever has improved in recent decades, with both an increase in the number and geographic representation of high-quality typhoid fever incidence studies, and greater sophistication of modeling approaches. The 2017 World Health Organization Strategic Advisory Group of Experts on Immunization recommendation for the introduction of typhoid conjugate vaccines for infants and children aged >6 months in typhoid-endemic countries is likely to require further improvements in our understanding of typhoid burden at the global and national levels. Furthermore, the recognition of the critical and synergistic role of water and sanitation improvements in concert with vaccine introduction emphasize the importance of improving our understanding of the sources, patterns, and modes of transmission of Salmonella Typhi in diverse settings.
Source: Clinical Infectious Diseases
DOI: 10.1093/cid/ciy846
Author: John A Crump
Institution: University of Otago
Language: English
Subfield: Food Science
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $3,532
Funders: National Science Foundation, Bill and Melinda Gates Foundation, Sabin Vaccine Institute, National Institutes of Health, Directorate for Biological Sciences, Biotechnology and Biological Sciences Research Council, National Science Foundation of Sri Lanka, National Institute of Allergy and Infectious Diseases, Fogarty International Center
Awards: G1591515831, Social, Economic and Environmental Drivers of Zoonoses in Tanzania (SEEDZ), G1886633764, G3028693477, G3168060087, G3204045353, The impact and social ecology of bacterial zoonoses in northern Tanzania, G4518260094, G4715098775, The Impact and Society Ecology of Bacterial Zoonoses in Northern Tanzania: Under, G5443035086, G55461420, University of Otago - to support and expedite the publication of previously unpublished data on the disease burden of typhoid and invasive non-typhoidal Salmonella (iNTS..., G7855057906, G8865120622, Investigating Febrile Deaths in Tanzania (INDITe)
OpenAlex ID: W2911861514