Work

Autophagy in Ovarian Follicular Development and Atresia

Year: 2019

Type: review

Abstract: Autophagy is a mechanism that exists in all eukaryotes under a variety of physiological and pathological conditions. In the mammalian ovaries, less than 1% of follicles ovulate, whereas the remaining 99% undergo follicular atresia. Autophagy and apoptosis have been previously found to be involved in the regulation of both primordial follicular development as well as atresia. The relationship between autophagy, follicular development, and atresia have been summarized in this review with the aim to obtain a more comprehensive understanding of the role played by autophagy in follicular development and atresia.

Source: International Journal of Biological Sciences

DOI: 10.7150/ijbs.30369

Authors: Jiawei Zhou, Xianwen Peng, Shuqi Mei

Institution: Hubei Academy of Agricultural Sciences

Language: English

Topic: Autophagy in Disease and Therapy

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,337