Year: 2019
Type: article
Abstract: We experimentally investigated the Cherenkov luminescence imaging (CLI) of the isotopes with different beta particles energies (Cu64, F18, Au198, P32, and Br76) in semitransparent biological equivalent media. The main focus of this work is to characterize the CLI when the sources are at the depth comparable with the range of beta particles. The experimental results were compared with Monte Carlo (MC) simulation results to fine tune the simulation parameters to better model the phantom materials. This approach can be applied to estimate the CLI performance for different phantom materials and isotopes. This work also demonstrates some unique properties of high energy beta particles that can be beneficial for CLI, including the possibility to utilize the betas escaped from the object for imaging purposes.
Source: Journal of Biomedical Optics
Authors: Sergey Komarov, Yongjian Liu, Yuan-Chuan Tai
Institution: Washington University in St. Louis
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,675
Awards: G133293143, TAS::89 0222::TAS; NEW; TITLE: DEVELOPMENT OF SIMULTANEOUS BETA-AND-COINCIDENCE-GAMMA IMAGES FOR PLANT IMAGING RESEARCH; PI: YUAN-CHUAN TAI, Collaborative Research on Plant Stress Response Through Innovations in Phenomics and Molecular Imaging Technologies, IVIS LUMINA II XR FOR OPTICAL IMAGING OF RADIOPHARMACEUTICALS
OpenAlex ID: W2913121691