Flavivirus serocomplex cross-reactive immunity is protective by activating heterologous memory CD4 T cells
Year: 2019
Type: article
Abstract: Purpose: How prior immunity influences immune memory recall and protection against related flaviviruses is largely unknown; yet encounter with multiple flaviviruses in a lifetime is increasingly likely. Here, we aimed to determine whether serocomplex cross-reactive immunity is detrimental during vaccination or if it can prime for protective immune responses.
Authors: W. Saron, A. Rathore, T. Lim, E.E. Ooi, J. Low, S. Abraham, A.L. St. John
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,750
OpenAlex ID: W2913785200