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Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets

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Year: 2019
Type: article
Source: Molecular Cell
DOI: 10.1016/j.molcel.2018.12.008
Authors: Kristen E. Mengwasser, Richard O. Adeyemi, Yumei Leng, Mei Yuk Choi, Connor Clairmont, Alan D. D’Andrea, Stephen J. Elledge
Institutions: Brigham and Women's Hospital, Howard Hughes Medical Institute, Harvard University, Dana-Farber Cancer Institute
Language: English

Topic: DNA Repair Mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: U.S. Department of Defense, Howard Hughes Medical Institute, Breast Cancer Research Foundation, Life Sciences Research Foundation, National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences
Awards: DNA REPAIR PATHWAYS AS TARGETS FOR TREATING BREAST CANCER, Medical Scientist Training Program, Analysis of the Mammalian DNA Damage Response
OpenAlex ID: W2914604310
FWCI: 7.618
Cites: 79
Cited by: 203
Related to: 10
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