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Non-invasive Imaging Methods for Brown Adipose Tissue Detection and Function Evaluation

Year: 2018
Type: article
Abstract: Brown Adipose Tissue (BAT) has a major role in thermoregulation, producing heat by non-shivering thermogenesis. Primarily found in animals and human infants, the presence of significant brown adipose tissue was identified only recently, and its metabolic role in adults was reconsidered. BAT is believed to have an important role in many metabolic diseases, such as obesity and diabetes, and also to be associated with cancer cachexia. Therefore, it is currently a topic of great interest in the research community, and many groups are investigating the mechanisms underlying BAT metabolism in normal and pathological conditions. However, well established non-invasive methods for assessing BAT distribution and function are still lacking. The purpose of this review is to summarize the current state of the art of these methods, with a particular focus on PET, CT and MRI.
DOI: 10.4172/2165-8048.1000299
Authors: Yaqi Zhang, Xiaofei Hu, Su Hu, Alessandro Scotti, Kejia Cai, Jian Wang, Xin Zhou, Ding Yang, Matteo Figini, Liang Pan, Junjie Shangguan, Jia Yang, Zhouli Zhang
Institutions: Northwestern University, Army Medical University, Southwest Hospital, First Affiliated Hospital of Soochow University, University of Illinois Chicago, Pingjin Hospital, University of Florida, Soochow University, Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Language: English
Subfield: Physiology
Field: Medicine
Open Access status: green
OpenAlex ID: W2914978962
FWCI: 0.343
Cites: 84
Cited by: 6
Related to: 10