Work

Immunoinflammatory mediators in the pathogenesis of diabetes mellitus

Year: 2019
Type: article
Abstract: Characterized as a metabolic syndrome with multiple consequences for the lives of patients, diabetes mellitus is also classified as a chronic non-communicable disease of great scope in the world. It is a complex disease, with different points of view, including the relation between inflammatory process, obesity and insulin resistance due to the performance of the various immunoinflammatory mediators - called adipokines - on glycemic homeostasis. Recent studies have precisely addressed this aspect for the development of drugs that assist in the protection of pancreatic ß cells from the damages arising from oxidative stress and inflammatory process, in order to control the hyperglycemic picture, which is characteristic of diabetes mellitus.
Language: Portuguese
Field: Medicine
Open Access status: diamond
OpenAlex ID: W2915571323
FWCI: 3.162
Cites: 26
Cited by: 35
Related to: 10