Work

HRAS‐driven cancer cells are vulnerable to TRPML1 inhibition

Year: 2019

Type: article

Source: EMBO Reports

DOI: 10.15252/embr.201846685

Authors: Jewon Jung, Kwang‐Jin Cho, Ali K Naji, Kristen N Clemons, Ching On Wong, Mariana Villanueva, Steven Gregory, Nicholas E Karagas, Lingxiao Tan, Hong Liang, Morgan A Rousseau, Kelly M Tomasevich, Andrew G Sikora, Ilya Levental, Dharini van der Hoeven, Yong Zhou, John F Hancock, Kartik Venkatachalam

Institutions: The University of Texas Health Science Center at Houston, Wright State University, The University of Texas MD Anderson Cancer Center, Baylor College of Medicine

Language: English

Topic: Calcium signaling and nucleotide metabolism

Subfield: Physiology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Cancer Prevention and Research Institute of Texas, National Institutes of Health, National Cancer Institute, National Institute of Neurological Disorders and Stroke

Awards: K-Ras plasma membrane interactions: a tractable therapeutic target, K-ras Spatiotemporal Dynamics: Novel Therapeutic Targets, G3682242222, GDAP1 mediated cellular damage in MLIV, Alterations in synaptic growth and lipid-raft organization in a fly MLIV model, G9000280502, Baylor College of Medicine Cancer Center - Cancer Center Support Grant

OpenAlex ID: W2917476711

FWCI: 7.973

Cites: 79

Cited by: 86

Related to: 10