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Mechanisms of MTH1 inhibition-induced DNA strand breaks: The slippery slope from the oxidized nucleotide pool to genotoxic damage

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Year: 2019
Type: review
Source: DNA repair
DOI: 10.1016/j.dnarep.2019.03.001
Authors: Priyamvada Rai, Robert W. Sobol
Institutions: University of Miami, Sylvester Comprehensive Cancer Center, University of South Alabama
Language: English

Topic: DNA Repair Mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute, National Institute of Environmental Health Sciences
Awards: MutT Homolog 1 as a Novel Mediator of RAS Oncogene-Induced Pro-Malignant Pathways, Measuring genomic DNA damage and DNA repair capacity in longitudinal population samples - a step towards precision prevention, Greater Caribbean Center for Ciguatera Research, Novel approaches to enhance tumor cell cytotoxicity of alkylating agents, A Systems Approach to Mapping the DNA Damage Response
OpenAlex ID: W2919657165
FWCI: 0.396
Cites: 126
Cited by: 29
Related to: 10
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