Work

Cardiomyopathy Mutations in Metavinculin Disrupt Regulation of Vinculin-Induced F-Actin Assemblies

Year: 2019

Type: article

Source: Journal of Molecular Biology

DOI: 10.1016/j.jmb.2019.02.024

Authors: Muzaddid Sarker, Hyunna T. Lee, Lin Mei, Andrey Krokhotin, Santiago Espinosa de los Reyes, Laura Yen, Lindsey M. Costantini, Jack Griffith, Nikolay V. Dokholyan, Gregory M. Alushin, Sharon L. Campbell

Institutions: University of North Carolina at Chapel Hill, UNC Lineberger Comprehensive Cancer Center, Rockefeller University, New York Structural Biology Center

Language: English

Topic: Cardiomyopathy and Myosin Studies

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Rockefeller University, The Ministry of Economic Affairs and Employment, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Environmental Health Sciences

Awards: Role of metavinculin in actin reorganization and force transmission, Mechanosensing Via Cytoskeletal Strain, DNA-Protein Interactions at the Replication Fork, The structure of the telomere as a sentinel of DNA damage., Integrating cheminformatics and molecular simulations for virtual drug screening, Engineering allostery for in vivo protein control, Role of the Tail Domain in Vinculin Function, Nucleoprotein Structures at Telomeres and Sites of DNA Damage, Mechanisms of vinculin activation and force transmission, G9000240336, Structure and Mechanism of G-proteins and cell adhesion proteins in regulation of cell growth and motility

OpenAlex ID: W2920271303

FWCI: 0.903

Cites: 48

Cited by: 16

Related to: 10