Work

Silanediol Anion Binding and Enantioselective Catalysis

Year: 2019

Type: article

Abstract: Silanediols possess unique and complementary catalytic activity in reactions that are likely to proceed through anion binding. This article directly compares silanediols, thioureas, and squaramides in three separate anion-binding processes. The catalytic abilities of select members of each family are directly correlated to association constant.

Source: Synthesis

DOI: 10.1055/s-0037-1612217

Authors: Jonathan Attard, Kohei Osawa, Yong Guan, Jessica Hatt, Shin-ichi Kondo, Anita Mattson

Institutions: Worcester Polytechnic Institute, Yamagata University

Language: English

Topic: Asymmetric Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences

Award: Silanediol Enabled Drug Discovery