Anticonvulsant prophylaxis and steroid use in adults with metastatic brain tumors: summary of SNO and ASCO endorsement of the Congress of Neurological Surgeons guidelines*
Year: 2019
Type: article
Abstract: BACKGROUND: The Congress of Neurological Surgeons (CNS) has developed a series of guidelines on the treatment of adults with metastatic brain tumors, including systemic therapy and supportive care topics. ASCO has a policy and set of procedures for endorsing clinical practice guidelines that have been developed by other professional organizations. METHODS: Two CNS Guidelines were reviewed for developmental rigor by methodologists and an independent multi-disciplinary Expert Panel was formed to review the content and assess agreement with the recommendations. The expert panel voted to endorse the two guidelines and ASCO and SNO independently reviewed and approved the ASCO/SNO guideline endorsement. RESULTS: The ASCO/SNO Expert Panel determined that the recommendations from the CNS anticonvulsants and steroids guidelines, published January 9, 2019, are clear, thorough, and based upon the most relevant scientific evidence. ASCO/SNO endorsed these two CNS guidelines, with minor alterations. CONCLUSIONS: Key recommendations include: prophylactic anti-epileptic drugs were not recommended for routine use; corticosteroids (specifically dexamethasone) were recommended for temporary symptomatic relief in patients with neurologic symptoms and signs related to mass effect from brain metastases.
Source: Neuro-Oncology
Authors: Susan M Chang, Hans Messersmith, Manmeet Ahluwalia, David Andrews, Priscilla K Brastianos, Laurie E Gaspar, Na Tosha N Gatson, Justin T Jordan, Mustafa Khasraw, Andrew B Lassman, Julia Maues, Maciej Mrugala, Jeffrey Raizer, David Schiff, Glen Stevens, Ashley Sumrall, Martin Van den Bent, Michael A Vogelbaum
Institutions: University of California, San Francisco, American Society of Clinical Oncology, Cleveland Clinic, Thomas Jefferson University, Massachusetts General Hospital, University of Colorado Anschutz, University of Colorado Denver, Geisinger Neuroscience Institute, The University of Sydney, Columbia University Irving Medical Center, Mayo Clinic, Mayo Clinic Hospital, Northwestern University, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, University of Virginia Medical Center, Levine Cancer Institute, Erasmus MC Cancer Institute
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2921879040