Work

Hepatitis C virus infection is a risk factor for non-Hodgkin lymphoma

Year: 2019

Type: review

Study designs: Systematic Review, Meta-Analysis

Abstract: Previous studies have reached conflicting results regarding the possibility that hepatitis C virus (HCV) infection may increase the risk of non-Hodgkin lymphoma (NHL). We performed a meta-analysis to clarify the relationship between HCV infection and development of NHL. The PubMed, Web of Science, and Embase databases were searched for relevant studies estimating the association between HCV infection and NHL risk through October 31, 2017. Fixed effects or random effects models were used to calculate the pooled odds ratio (OR) and its 95% confidence interval (CI). A total of 18 studies met the inclusion criteria. We found a positive association between HCV infection and NHL (pooled OR 1.69, 95% CI 1.40-2.03, P < .05). In conclusion, our meta-analysis suggested that HCV infection was associated with increased risk of developing NHL.

Source: Medicine

DOI: 10.1097/md.0000000000014755

Authors: Xiaofeng Zhu, Li Jing, Xiaoming Li

Institutions: Southwest Medical University, Affiliated Hospital of Southwest Medical University

Language: English

Topic: Hepatitis C virus research

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,950