Dietary calcium intake and the risk of metabolic syndrome: evidence from observational studies
Year: 2019
Type: article
Study designs: Systematic Review, Meta-Analysis
Abstract: OBJECTIVE: Epidemiological investigations evaluating the association of dietary Ca intake with metabolic syndrome (MetS) risk have yielded controversial results. Therefore, a meta-analysis was conducted to quantitatively summarize the association between dietary Ca intake and the risk of MetS. DESIGN: PubMed, Embase and Web of Science were searched for relevant articles published up to October 2018. The pooled OR and 95 % CI were calculated with a random-effects model. SETTING: Meta-analysis.ParticipantsNine cross-sectional studies. RESULTS: A total of nine articles with fifteen studies for dietary Ca intake were finally included in the meta-analysis. The combined OR with 95 % CI of MetS for the highest v. lowest category of dietary Ca intake was 0·80 (95 % CI 0·70, 0·91). For dose-response analysis, a non-linear relationship was found between dietary intake of Ca and risk of MetS (P non-linearity<0·001). The threshold for dietary Ca intake was 280 mg/d (OR=0·87; 95 % CI 0·82, 0·93), reducing the risk of MetS by 13 %. CONCLUSIONS: The present meta-analysis suggests that dietary Ca intake might reduce the risk of MetS, which needs to be further confirmed by larger prospective cohort studies.
Source: Public Health Nutrition
Authors: Lixiao Cheng, Danqing Hu, Wenjie Jiang
Institution: Qingdao University
Language: English
Topic: Nutritional Studies and Diet
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2922217997