Work

Targeting the Second Bromodomain (BDII) of BET Family with Abbv-744 Results in Robust Anti-Leukemia Activity in AML Models with Excellent In Vivo Tolerability

Year: 2018

Type: conference-abstract

Source: Blood

DOI: 10.1182/blood-2018-99-116912

Authors: Tianyu Cai, Vinitha Mary Kuruvilla, Tamar Uziel, Qi Zhang, Lina Han, Antonio Cavazos, Yu Shen, Marina Y. Konopleva, Xiaoyu Lin, Xin Lu, Lu Zhang

Institutions: The University of Texas MD Anderson Cancer Center, AbbVie (United States)

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W2922548931

Cites:

Cited by: 1

Related to: 10