Comparative effects of granulocyte-colony stimulating factor and colistin-alone or in combination on burn wound healing in Acinetobacter baumannii infected mice.
Year: 2018
Type: article
Abstract: BACKGROUND AND OBJECTIVES: ) infected burns. MATERIALS AND METHODS: . In a 7-day period, burn wounds in each group were daily treated with subcutaneous injections (0.1 ml) of saline, G-CSF, colistin, and G-CSF plus colistin. After killing the animals, the size of the wound, number of leukocytes in the skin and microbial growth were evaluated. A value of p ≤ 0.05 was considered statistically significant. RESULTS: day of treatment, number of positive bacterial cultures in the colistin and the G-CSF plus colistin groups was lower than other groups with a significant difference. CONCLUSION: Concurrent consumption of G-CSF and antibiotics can control burn infection and enhance the immune system towards wound healing.
Source: Europe PMC (PubMed Central)
Language: English
Topic: Wound Healing and Treatments
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2922973540