Designing an Individually Tailored Multilevel Intervention to Increase Engagement in HIV and Substance Use Treatment Among People Who Inject Drugs With HIV: HPTN 074
Year: 2019
Type: article
Abstract: People who inject drugs (PWID) face barriers to engagement in antiretro-viral treatment (ART) and medication-assisted treatment (MAT). We detail the design, rapid preparation and adaptation, and systematic implementation of a flexible, individually tailored intervention for PWID in multiple settings: Indonesia, Ukraine, and Vietnam. HPTN 074 integrated systems navigation and counseling to facilitate entry and adherence to ART and MAT. Site-level guidance on the intervention involved in-depth interviews (IDIs) among PWID and their supporters and site-specific document review. IDIs emphasized ART misinformation and importance of social support for adherence. The document review revealed differences in health care system barriers, requiring an intervention that was flexible and tailored enough to address key outcomes. Implementation included regular debriefs for iterative adaptations based on participants' needs, including booster counseling sessions and subsidizing pre-ART testing. HPTN 074 provides a unique framework implementing a flexible and scalable intervention to improve ART and MAT outcomes among PWID across multiple settings.
Source: AIDS Education and Prevention
Institutions: The Ohio State University, Ukrainian Institute of Public Health Policy, Universitas Jakarta Internasional, University of North Carolina at Chapel Hill, Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo, Treatment Research Institute, University of Pennsylvania, Johns Hopkins University
Language: English
Topic: HIV, Drug Use, Sexual Risk
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: G1005250088, G1077701788, G115026442, G1310891712, G1939027404, G1951574862, G2127051194, G2230551448, G2993261131, G3598573620, G637192391, G654751394, G6757287288, G793395730, G8541996175, G9000027606, G9000035439, G9000036922, G9000072712, G9000075494, Penn Mental Health AIDS Research Center, G95499620, G95938990
OpenAlex ID: W2923322940
