Work

Association of G/C (rs638405) Polymorphism in β-secretase Gene with Alzheimer's Disease.

Year: 2018

Type: article

Abstract: BACKGROUND: gene with sporadic AD in Khuzestan, Isfahan and Fars provinces in Iran. METHODS: Genotypes were determined by the PCR-Restriction Fragment Length Polymorphism (PCR-RFLP) technique in two groups including 89 sporadic AD patients and 73 healthy subjects. RESULTS: =3.333, df=1, p=0.068). CONCLUSION: gene might not be related with sporadic AD in Khuzestan, Isfahan and Fars provinces in Iran. However, our results do not support a genetic risk factor of this polymorphism for developing AD in male group of this study.

Source: Europe PMC (PubMed Central)

Authors: Mostafa Chashmpoosh, Hossein Babaahmadi, Rouhollah Mousavidehmordi, Bita Shalbafan, Asma Mohammadi, Alireza Kheirollah

Institution: Ahvaz Jundishapur University of Medical Sciences

Language: English

Topic: Alzheimer's disease research and treatments

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2924107668

FWCI:

Cites: 36

Cited by: 1

Related to: 10