Year: 2012
Type: conference-paper
Abstract: We present the first demonstration of a novel bacterial biofilm treatment technique showing a 56% average decrease in bacterial cell viability compared to traditional antibiotic treatments in a Micro-BOAT platform.Integrated linear array charge-coupled devices achieve spatially realized optical density monitoring, correlating to both average biomass and localized biofilm morphology.For on-chip demonstration of biofilm treatment, a unique bioelectric effect using a superpositioned direct and alternating current electric field is applied in the presence of antibiotics.Use of the platform demonstrated successful real-time monitoring of biofilm treatment and validated an on-chip bioelectric effect showing a decrease in both bacterial cell viability and overall biomass.
Institution: University of Maryland, College Park
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2926011398