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Targeting SOCS Proteins to Control JAK-STAT Signalling in Disease

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Year: 2019
Type: review
Source: Trends in Pharmacological Sciences
DOI: 10.1016/j.tips.2019.03.001
Authors: Gillian A. Durham, Jamie J.L. Williams, M. Talat Nasim, Timothy M. Palmer
Institutions: University of Bradford, University of Glasgow, University of Hull, Hull York Medical School
Language: English

Topic: Cytokine Signaling Pathways and Interactions
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: British Heart Foundation, Royal Society, Great Britain Sasakawa Foundation
Awards: Inhibition of vascular STAT signalling by AMP-activated protein kinase (AMPK), Prostanoid-mediated inhibition of IL-6 trans- signalling in pulmonary arterial hypertension: a role for epac1 mediated induction of 'Suppressor of Cytokine Signalling 3' (SOCS3), Suppression of IL-6 trans signalling by BMP4: a ‘missing link’ in the development of pulmonary arterial hypertension?, G8820320403
OpenAlex ID: W2927217388
FWCI: 1.635
Cites: 59
Cited by: 183
Related to: 10
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