Work

Biomimetics: Antimicrobial Microwebs of DNA–Histone Inspired from Neutrophil Extracellular Traps (Adv. Mater. 14/2019)

Year: 2019

Type: article

Abstract: Inspired by the macromolecular weapons used by a type of white blood cell to capture and kill bacteria, in article number 1807436, J. Scott VanEpps, Shuichi Takayama, and co-workers engineer nanofibrillar microwebs composed of DNA and histones that mimic neutrophil extracellular traps (NETs). The microwebs can enhance the killing activity of a last-resort antibiotic against Escherichia coli even when it harbors a resistance gene.

Source: Advanced Materials

DOI: 10.1002/adma.201970097

Authors: Yang Song, Usha Kadiyala, Priyan Weerappuli, Jordan J. Valdez, Srilakshmi Yalavarthi, Cameron Louttit, Jason S. Knight, James J. Moon, David S. Weiss, J. Scott VanEpps, Shuichi Takayama

Institutions: Georgia Institute of Technology, The Wallace H. Coulter Department of Biomedical Engineering, University of Michigan, Michigan Medicine, Emory University

Language: English

Topic: Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W2928040334

FWCI:

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