Work

Pervasive Pairwise Intragenic Epistasis among Sequential Mutations in TEM-1 β-Lactamase

Year: 2019

Type: article

Source: Journal of Molecular Biology

DOI: 10.1016/j.jmb.2019.03.020

Authors: Courtney E. Gonzalez, Marc Ostermeier

Institution: Johns Hopkins University

Language: English

Topic: Evolution and Genetic Dynamics

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: National Institutes of Health, National Science Foundation of Sri Lanka, National Institute of General Medical Sciences

Awards: G3658654797, Experimentally-determined fitness landscape of beta-lactamase inhibitory protein, G6104945536, G8597855816

OpenAlex ID: W2928861204

FWCI: 2.854

Cites: 42

Cited by: 52

Related to: 10