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Computational Redesign of PD-1 Interface for PD-L1 Ligand Selectivity

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Year: 2019
Type: article
Source: Structure
DOI: 10.1016/j.str.2019.03.006
Authors: Rojan Shrestha, Sarah C. Garrett, Steven C. Almo, Andras Fiser
Institution: Albert Einstein College of Medicine
Language: English

Topic: Cancer Immunotherapy and Biomarkers
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: National Science Foundation, National Institutes of Health, National Human Genome Research Institute, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases
Awards: Molecular basis of recognition in the Immunological Synapse, Molecular basis of receptor-ligand recognition in the Immunological Synapse, Technologies for Mapping the Extracellular Interactome, Interdisciplinary protein engineering approach to design high affinity antibodies for flaviviruses, XSEDE: eXtreme Science and Engineering Discovery Environment
OpenAlex ID: W2929848311
FWCI: 0.938
Cites: 65
Cited by: 16
Related to: 10
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