Inflammatory, metabolic, and vascular changes upon high-fat diet feeding and n-3 LCPUFA supplementation in mice
Year: 2018
Type: dissertation
Abstract: In this thesis, mice, fed defined high-fat diet (HF) or n-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA)-enriched HF to induce obesity, were analysed. Differential changes for immune cell markers, enzymes of the fatty acid metabolism and proteins maintaining vascular integrity were found in different tissues upon 12-week feeding. The expression and immunohistochemical data support immunomodulatory and anti-obesogenic effects of n-3 LCPUFA observed previously in this mouse study.
Author: Worsch, Stefanie
Language: English
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Open Access status: green
Funder: Deutsche Forschungsgemeinschaft
OpenAlex ID: W2934105484
