Work

Stereoselective Oxidation Kinetics of Deoxycholate in Recombinant and Microsomal CYP3A Enzymes: Deoxycholate 19-Hydroxylation Is an In Vitro Marker of CYP3A7 Activity

Year: 2019

Type: article

Source: Drug Metabolism and Disposition

DOI: 10.1124/dmd.119.086637

Authors: Yu-Jie Chen, Jian Zhang, Ping-Ping Zhu, Xian-Wen Tan, Qiu-Hong Lin, Wen-Xia Wang, Shan-Shan Yin, Ling-Zhi Gao, Ming-Ming Su, Chang-Xiao Liu, Liang Xu, Wei Jia, Irina F. Sevrioukova, Ke Lan

Institutions: University of California, Irvine, Sichuan University, Tianjin Institute of Pharmaceutical Research (China), University of Hawaii Cancer Center, State Key Laboratory of Pharmacokinetics and Drug Delivery Technology

Language: English

Topic: Pharmacogenetics and Drug Metabolism

Subfield: Pharmacology

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Institute of Environmental Health Sciences

Award: Toxicological importance of CYP3A4 catalysis and inhibition

OpenAlex ID: W2934688564

FWCI: 4.018

Cites: 41

Cited by: 21

Related to: 10