Work

The role of RASSF proteins in modulating RAS driven lung tumors in vivo

Year: 2019

Type: article

Abstract: Sir, the recent editorial of our article describing the first animal model for KRAS-driven lung tumors in a RASSF1A-deficient background (1) succinctly and accurately describes our work. I would like to take the opportunity to elaborate and to describe some additional pertinent experiments.

Source: Journal of Thoracic Disease

DOI: 10.21037/jtd.2019.03.60

Authors: Katherine Hobbing, M. Lee Schmidt, Howard Donninger, Geoffrey J. Clark

Institution: University of Louisville

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: National Cancer Institute, National Institute of Environmental Health Sciences