Work

Total Synthesis of Aspidosperma and Strychnos Alkaloids through Indole Dearomatization

Year: 2019

Type: article

Abstract: Monoterpenoid indole alkaloids are the major class of tryptamine-derived alkaloids found in nature. Together with their structural complexity, this has attracted great interest from synthetic organic chemists. In this Review, the syntheses of Aspidosperma and Strychnos alkaloids through dearomatization of indoles are discussed.

Source: Chemistry - A European Journal

DOI: 10.1002/chem.201901130

Authors: Jordy M. Saya, Eelco Ruijter, Romano V. A. Orru

Institution: Vrije Universiteit Amsterdam

Language: English

Topic: Alkaloids: synthesis and pharmacology

Subfield: Pharmacology

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

Open Access status: green

Funder: Nederlandse Organisatie voor Wetenschappelijk Onderzoek

OpenAlex ID: W2938718560

FWCI: 18.21

Cites: 285

Cited by: 156

Related to: 10