Cystic Fibrosis Rapid Response: Translating Multi-omics Data into Clinically Relevant Information
Year: 2019
Type: article
Abstract: Proper management of polymicrobial infections in patients with cystic fibrosis (CF) has extended their life span. Information about the composition and dynamics of each patient’s microbial community aids in the selection of appropriate treatment of pulmonary exacerbations. We propose the cystic fibrosis rapid response (CFRR) as a fast approach to determine viral and microbial community composition and activity during CF pulmonary exacerbations. The CFRR potential is illustrated with a case study in which a cystic fibrosis fatal exacerbation was characterized by the presence of shigatoxigenic Escherichia coli . The incorporation of the CFRR within the CF clinic could increase the life span and quality of life of CF patients.
Source: mBio
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,900
Funder: Argonne National Laboratory
OpenAlex ID: W2939196448