Autophagy Targeted Curation
Year: 2019
Type: other
Abstract: Autophagy is the lysosomal degradative process of cellular components and is essential for cell survival, differentiation, development and homeostasis. Dysfunctional autophagy results in various pathologies including neurodegenerative diseases, infectious diseases and cancers. Reactome is a freely available manually curated human pathway database that provides an interactive service to search, investigate and download data. Reactome provides thoroughly curated, annotated and reviewed information on the autophagy pathway. Every mechanistic detail in the process is curated and annotated with reference literatures that contain experimental confirmation. Users can treat Reactome as a start point to swiftly understand the complex biology of autophagy at a molecular level. Additionally, analysis tools in Reactome can be used to investigate empirical data. Taken together, Reactome provides a one-stop pathway guide and analysis platform of currently established autophagy mechanisms for researchers and clinicians.
Institution: European Bioinformatics Institute
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W2939212113