Work

Early-life vancomycin treatment promotes airway inflammation and impairs microbiome homeostasis

Year: 2019

Type: article

Abstract: were potentially correlated to the severity of allergic airway inflammation. Our study suggests that perinatal and early-life vancomycin intervention aggravates allergic inflammation in adulthood, which might be correlated with imbalanced gut and lung microbiome homeostasis.

Source: Aging

DOI: 10.18632/aging.101901

Authors: Xin Yang, Hanrong Feng, Xueqin Zhan, Chao Zhang, Rui Cui, Lijia Zhong, Songmin Ying, Zhimin Chen

Institutions: Children's Hospital of Zhejiang University, Zhejiang University, Second Affiliated Hospital of Zhejiang University

Language: English

Topic: Asthma and respiratory diseases

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Natural Science Foundation of China, Zhejiang Provincial Program for the Cultivation of High-Level Innovative Health Talents, Natural Science Foundation of Zhejiang Province

Awards: G1892322902, E3泛素连接酶FBXW7通过负向调控巨噬细胞M2极化抑制哮喘发病及其机制研究, 有丝分裂期DNA修复导致肿瘤化疗耐药的分子机制及潜在干预靶点研究, 炎症细胞中DNA损伤对肺损伤的免疫调控作用机制研究

OpenAlex ID: W2940387978

FWCI: 1.719

Cites: 42

Cited by: 24

Related to: 10