The Effects of Lifestyle Modification and HMG-Coa Reductase Inhibitor Treatment on Blood Tumor Necrosis Factor-Like Weak Inducer of Apoptosis (TWEAK) Levels Among Patients with Isolated Hypercholesterolemia
Year: 2018
Type: article
Abstract: Isolatedhypercholesterolemia is a frequent condition in the general population. It is managedmostly by therapeutic lifestyle intervention and/or statin treatment. TWEAK isa cytokine from the TNF superfamily and plays a role in tissue regeneration inacute period; it is also involved in tissue damage in chronic period. In thisstudy, we investigated plasma TWEAK levels of participants with isolated LDLcholesterol elevation in response to first 12 weeks of lifestyle modification,and 12 weeks of statin treatment. In conclusion, plasma sTWEAK level increasedin dyslipidemia patients who were able to reach target LDL levels aftertherapeutic lifestyle modification. However, correcting dyslipidemia withstatin was not associated with any change in plasma sTWEAK level.
Source: DergiPark (Istanbul University)
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2941070715